Atlas of Variant Effects Alliance :
Precision medicine at nucleotide resolution
Art by Uta Mackensen (CC BY-ND) Image Description: Background: A world map and chromosome idiogram. Foreground: People moving amongst and inspecting larger than life Variant Effect Maps of clinically important genes BRCA1, HMBS, MTHFR and TDP-43.
The vision of the Alliance is to create comprehensive variant effect maps for important regions of human and human pathogen genomes that could ultimately assist in the diagnosis, prognosis and treatment of disease. The goal of our Alliance is to bring together data generators, curators and consumers, along with funders and other stakeholders, to set standards, share tools and develop strategy.
“By describing the effects of variants in the genome, the atlas will accelerate and empower biological research, drug discovery and medical practice.”
Graphic Credits: kjpargeter Freepik, Sayeh Gorjifard and Uta Mackensen