The genetic architecture of protein function
Alexandra Bendel (she/her)
Ecole Polytechnique Fédérale de Lausanne (EPFL)
Presentation Date: 4 February 2025
I grew up in the Black Forest in Germany and got my Bachelor’s and Master’s degrees in Genetics and Developmental Biology from the University of Freiburg in Germany.
For my PhD, I joined Guillaume Diss’ lab at the Friedrich Miescher Institute for Biomedical Research in Basel, Switzerland, where I got into the topic of Network Biology and Deep Mutational Scanning.
I graduated in December 2023 and soon after joined the lab of Professor Nicolas Thomae at the EPFL in Lausanne, Switzerland, as a Postdoc. Here, I am now trying to apply my skills in high-throughput screening of protein interactions to study molecular glues, small molecules that can induce novel interactions between proteins, specifically proteins and E3 ubiquitin ligases which can then result in the degradation of said proteins in a disease context.